Estradiol Valeate tablet
What is it used for?
ESTRADIOL is an estrogen. It is mostly used as hormone replacement for menopausal women. It helps to treat hot flashes and prevent osteoporosis. It is also used to treat women with low estrogen levels or those who have had their ovaries removed.
What should I discuss with my physician prior to taking this medicine?
They need to know if you have or ever had any of these conditions:
- abnormal vaginal bleeding
- blood vessel disease or blood clots
- breast, cervical, endometrial, ovarian, liver, or uterine cancer
- gallbladder disease
- heart disease or recent heart attack
- high blood pressure
- high cholesterol
- high level of calcium in the blood
- kidney diseases
- liver diseases
- migraine headaches
- systemic lupus erythematosus (SLE)
- tobacco smoker
- an unusual or allergic reaction to estrogens, other hormones, medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How is this medicine should be taken?
Take this medicine orally. To reduce nausea, this medicine may be taken with food. Take this medicine at the same time each day and in the order directed on the package. You should never take this medicine more often than prescribed.
Overdosage: If you suspect an overdosage, get in touch with the nearest poison control center or emergency room immediately.
NOTE: This medicine is only intended for your use. You should never share it with the others.
What to do if I missed a dose?
If you missed a dose, it should be taken as soon as possible. If the time has almost come for the next dose, only that one should be taken. You should never take double or extra doses; a single doze is sufficient for the purposes.
What are the possible interactions with the other medicine/food/etc?
This medicine should never be taken with any of the following drugs:
- aromatase inhibitors like aminoglutethimide, anastrozole, exemestane, letrozole, testolactone
It may also trigger possible interactions with the following:
- certain antibiotics used to treat infections
- certain barbiturates or benzodiazepines used for inducing sleep or treating seizures
- grapefruit juice
- medicines for fungus infections like itraconazole and ketoconazole
- raloxifene or tamoxifen
- rifabutin, rifampin, or rifapentine
- St. John's Wort
This list is not all-inclusive. Provide your health care provider with a list of all the medicines, herbs, non-prescription drugs, or dietary supplements that you use. Also tell them whether you smoke, drink alcohol, or use illegal drugs. Some of those items may also interact with your medicine.
Is there anything I should pay attention to while taking it?
Pay regular visits to your doctor or health care professional to undergo checks on your progress. You will need a regular breast and pelvic exam and Pap smear while on this medicine. You should also discuss the need for the regular mammograms with your health care professional, and follow their guidelines for these tests.
This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.
If you have any reason to think you are pregnant, stop taking this medicine right away and contact your doctor or health care professional.
Smoking increases the risk of getting a blood clot or having a stroke while you are taking this medicine, especially if you are older than 35 years old. You are strongly advised not to smoke.
If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye doctor or health care professional.
This medicine can increase the risk of developing a condition (endometrial hyperplasia) that may lead to a cancer of the lining of the uterus. Taking progestins, another hormone drug, with this medicine lowers the risk of developing this condition. Therefore, if your uterus has not been removed (by a hysterectomy), your doctor may prescribe a progestin for you to take together with your estrogen. You should know, however, that taking estrogens with progestins may have additional health risks. You should discuss the use of estrogens and progestins with your health care professional to determine the benefits and risks for you.
If you are going to have a surgery, you may need to stop taking this medicine. Consult with your health care professional for advice before scheduling the surgery.
Does this medicine have any possible side effects?
The following side effects should be reported to your doctor or health care professional as soon as they are noticed:
- allergic reactions like skin rashes, itching or hives,face, lips, or tongue swelling
- breast tissue changes or discharge
- changes in vision
- chest pains
- confusion, trouble speaking or understanding
- dark urine
- general ill feeling or flu-like symptoms
- light-colored stools
- nausea, vomiting
- pain, swelling, warmth in the leg
- right upper belly pain
- severe headaches
- shortness of breath
- sudden numbness or weakness of the face, arm or leg
- trouble walking, dizziness, loss of balance or coordination
- unusual vaginal bleeding
- yellowing of the eyes or skin
The below side effects usually do not necessarily require any medical attention (please do report them to your physician if they are recurrent or bothersome):
- hair loss
- increased hunger or thirst
- increased urination
- symptoms of vaginal infection like itching, irritation or unusual discharge
- unusual weakness or feeling tired
Other side effects are also possible, the above list is not all inclusive.
Where should I keep my medicine?
Keep this medicine out of the children’s reach.
This medicine should be stored at the room temperatures between 20 and 25 degrees C (68 and 77 degrees F). Keep container tightly closed. Store it away from the light. Dispose of any unused medicine after the expiry date is reached.